H. Pylori Testing Made Simple: Your Solution for Quick And Reliable Diagnosis

H. Pylori Testing Made Simple: Your Solution for Quick And Reliable Diagnosis

About Helicobacter Pylori

Helicobacter pylori (H. pylori) is a Gram-negative, spiral-shaped, microaerophilic bacterium that mainly infects the human gastric mucosa and is one of the main causes of a variety of gastric diseases.

Infection route

Helicobacter pylori is mainly transmitted through oral-oral, fecal-oral and shared tableware. Poor food hygiene, crowded places and shared tableware among family members are all factors that increase the risk of infection.

Common symptoms

Although some infected people may have no obvious symptoms, H. pylori infection is often associated with the following symptoms and illnesses:

1. Gastritis: Long-term infection can lead to chronic gastritis, causing symptoms such as stomach discomfort, bloating, and nausea.

2. Gastric ulcer and duodenal ulcer: The risk of ulcers in infected people is significantly increased, and symptoms such as stomach pain and burning sensation may occur.

3. Gastric cancer: Helicobacter pylori is classified as a Class I carcinogen by the World Health Organization (WHO). Long-term infection may increase the risk of gastric cancer.

4. Gastric mucosa-associated lymphoid tissue lymphoma (MALT lymphoma): Helicobacter pylori infection may also cause this rare cancer of the stomach.

Main diagnostic test methods

It is mainly divided into two categories: Invasive testing (requiring gastroscopy) and Non-invasive testing (not requiring gastroscopy).

1. Non-invasive detection methods

①. Urea breath test (UBT)

Principle: Helicobacter pylori can secrete a large amount of urease. After the patient takes a urea solution labeled with carbon isotopes (13C or 14C), Helicobacter pylori decomposes urea to produce carbon dioxide. The isotope change of carbon dioxide is detected by exhalation to determine whether the infection is present.

②. Fecal antigen detection

Principle: Detect whether there is Helicobacter pylori antigen in the patient's feces, usually using immunochromatography or enzyme-linked immunosorbent assay (ELISA).

③. Serological test (antibody test)

Principle: Determine the infection status by detecting Helicobacter pylori antibodies (IgG, IgA) in serum.

④. Saliva and urine antibody test

Principle: Detect Helicobacter pylori antibodies in saliva or urine to determine whether there is infection.

2. Invasive detection methods

①. Gastroscopy biopsy

Principle: Gastroscopy is used to collect gastric mucosal samples for testing, which is the "gold standard" for diagnosing Helicobacter pylori infection.

②. Molecular biology detection (PCR)

Principle: Detect Helicobacter pylori DNA in gastric mucosal samples through polymerase chain reaction (PCR).

Comparison of detection methods

Method	Advantages	Disadvantages
UBT	Non-invasive, highly sensitive and specific	Inconvenient sample handling, false negative results
Antibody testing	Simple and suitable for large-scale screening	Cannot distinguish between current and past infection
Saliva or urine antibody test	Non-invasive and suitable for all groups of people	Low sensitivity and specificity
Endoscopic biopsy	The “gold standard” for diagnosis and drug sensitivity testing	Invasive procedure, high cost
PCR molecular testing	High sensitivity, capable of detecting drug resistance genes	Sample collection requires gastroscopy and is expensive
Stool antigen test	Non-invasive and suitable for all groups of people	Inconvenient sample handling, false negative results

BioTeke H. Pylori Rapid Diagnostic Solution

Bioteke Helicobacter pylori Antigen Rapid Test Kit is an in vitro qualitative diagnostic product for rapid detection of Helicobacter pylori antigen in human fecal samples. 

It uses immunochromatography, which is simple to operate, fast and accurate, and is currently one of the common methods widely used to screen Helicobacter pylori infection.

Product Features

1. Rapid detection: Get test results within 15 minutes. No need to wait.

2. High sensitivity and specificity: Test samples can detect low concentrations of H. pylori antigens, reducing missed detection. Test sample accuracy rate 98.8%

3. Non-invasive sampling: Use stool samples, no gastroscopy or blood sampling is required.

4. Simple operation: No special equipment is required, suitable for use in homes, clinics and other scenarios.

5. Easy to read results: Read the results by eye, and positive and negative results are clearly visible.

Summary

Helicobacter pylori infection may exist in the human body for a long time without being detected, but it is an important cause of many stomach diseases, especially serious diseases such as gastric ulcers and gastric cancer. Timely detection and treatment of Helicobacter pylori infection is an important measure to protect stomach health.