Extraction of DNA, RNA, and proteins is a fundamental method used in molecular biology. These biomolecules can be isolated from any biological material for subsequent downstream processing, analytical or preparative purposes. In the past, the extraction and purification process of nucleic acid was complicated, time-consuming, laborious, and the overall throughput was limited. Currently, there are many specialized methods available for the extraction of pure biomolecules, such as solution-based and column-based protocols. Manual methods have come a long way over time, and various commercial products include complete kits containing most of the components needed to isolate nucleic acids, but most of these require repeated centrifugation steps followed by Sample type Removal of supernatant and additional mechanical processing. In recent years, there has been a growing demand for automation systems designed for medium and large laboratories. It is an alternative to labor-intensive manual m