Freeze-dried PCR Reagents Facilitate Multiple STDs Screening And Detection

Freeze-dried PCR Reagents Facilitate Multiple STI Screening And Detection

Sexually transmitted infections (STIs) are one of the major challenges to global public health, affecting millions of people every year. 

Sexually transmitted diseases include gonorrhea, chlamydia, syphilis, herpes and other pathogens, which are often hidden and may lead to serious consequences such as infertility, ectopic pregnancy and neonatal infection. 

Therefore, rapid and accurate diagnosis of sexually transmitted diseases is crucial for early intervention and effective treatment. Based on this demand, Bioteke Corporation has developed a sexually transmitted infection screening test kit that uses fluorescent PCR technology to detect nucleic acids of multiple sexually transmitted pathogens.

A. Background

• Traditional STD detection methods mainly include culture method, enzyme-linked immunosorbent assay (ELISA), rapid antigen test and nucleic acid amplification test (NAATs).

• However, although the culture method can provide accurate test results, it is time-consuming and has high requirements for the laboratory; although the antigen detection method is rapid, it has low sensitivity and cannot detect multiple pathogens at the same time.

• With the development of molecular biology technology, nucleic acid amplification detection technology has gradually become an important tool for diagnosing sexually transmitted diseases. Fluorescence PCR, as a highly sensitive and specific nucleic acid detection technology, can detect a variety of sexually transmitted pathogens in a short time.

Based on this, Bioteke Corporation has combined market demand and clinical pain points to carry out the research and development of STD infection screening test kits, and is committed to providing a simple operation, rapid results and high sensitivity for the clinic. Multiple pathogen detection solutions.

B. Research Results and Product Analysis

Bioteke STI screening kit can simultaneously detect 14 types of sexually transmitted pathogens, including trichomonas vaginalis, neisseria gonorrhoeae, chlamydia trachomatis, gardnerella vaginalis, haemophilus ducreyi, candida albicans, streptococcus agalactiae, ureaplasma urealyticum, ureaplasma parvum, mycoplasma hominis, mycoplasma genitalium, treponema pallidum, herpes simplex virus type 1&2.

The kit uses fluorescent PCR technology and has the following advantages:

• Multiple screening: It can detect multiple sexually transmitted infection pathogens in one test, reducing the waiting time for patients and improving diagnostic efficiency.

• High sensitivity and specificity: This product is a TaqMan® qPCR detection system based on multiple fluorescent probes. Specific primers and probes are used, which has extremely high sensitivity and specificity, can detect extremely low concentrations of pathogen nucleic acids, and reduce the risk of false negatives.

• Rapid detection: Compared with traditional culture methods, PCR detection only takes about 30-40 minutes to get results, which is suitable for clinical rapid screening needs.

  
  

• Easy operation: The kit is concisely designed and the operation steps are optimized. The Taqenzyme, UDGenzyme, reaction buffer, specific primers and probes required for the amplification experiment have been placed in the PCR tube in advance, reducing the difficulty of operation for laboratory technicians.

C. Clinical significance

In clinical applications, the significance of the STD infection screening test kit cannot be ignored. 

First, it improves the accuracy of STD diagnosis, allowing doctors to provide patients with personalized treatment plans more quickly and avoid misdiagnosis or missed diagnosis. 

Second, the kit is suitable for a variety of medical settings, including hospitals, disease control centers, and clinical laboratories, especially in resource-limited areas, and can provide strong technical support for large-scale screening.

At the same time, multiple pathogen detection reduces the number of repeated sampling, which not only increases the comfort of patients, but also improves the detection efficiency of medical institutions. Through the simultaneous detection of multiple sexually transmitted pathogens, doctors can have a more comprehensive understanding of the patient's infection status, so as to better formulate treatment plans and reduce the risk of STD transmission.

Future Outlook

With the continuous advancement of molecular biology technology, the diagnosis of sexually transmitted infections will become more accurate, convenient and economical. In the future, Bioteke Corporation plans to continue to optimize STD screening test kits and increase the detection capabilities of more sexually transmitted pathogens, such as HIV and human papillomavirus (HPV), to cover a wider spectrum of sexually transmitted diseases. 

In addition, the company will also focus on developing STD detection products for home use, so that more patients can test themselves and seek medical treatment early under the protection of privacy.

Bioteke's R&D team will also further explore how to improve the sensitivity and convenience of STD detection through emerging methods such as high-throughput sequencing technology or nanotechnology, and help the prevention and control of STDs in the public health field. 

At the same time, through cooperation with global medical experts and research institutions, Bioteke will continue to promote the standardization and popularization of STD screening, promote the global application of molecular diagnostic technology, and help more patients get the opportunity for early diagnosis and timely treatment.